How to use the gc skew calculator
Find the GC skew of a DNA sequence from its counts of G and C bases. Enter count of g bases, count of c bases in the fields above; the gc skew, strand bias are computed instantly and plotted on the chart so you can see how the answer changes.
Common searches this calculator answers include “GC skew”, “leading strand bias”, “G minus C over G plus C”, “calculate gc skew”, “find gc skew”.
Formula
Variables
- G — Count of G bases
- C — Count of C bases
Worked example
With count of g bases = 320, count of c bases = 180, the calculator gives gc skew ≈ 0.28; strand bias ≈ G-rich strand text.
Frequently asked questions
What is the gc skew calculator used for?
Find the GC skew of a DNA sequence from its counts of G and C bases. It helps with questions such as “GC skew”, “leading strand bias”, “G minus C over G plus C”.
What is the formula for the gc skew calculation?
GC skew = (G-C) / (G+C). Strand bias (text) = [GC skew]>0?"G-rich strand":"C-rich strand". Here G is count of g bases, C is count of c bases.
What inputs do I need for the gc skew calculator?
You need count of g bases, count of c bases. Each field is pre-filled with a typical example so you can see how the result responds as you edit the numbers.
How do I use the gc skew calculator?
Type values into the input fields. Results and the chart update instantly. Use Reset to restore the example values, Copy results to paste them elsewhere, or Share to copy a link that preserves your inputs.
Is the gc skew result exact?
Calculations use standard formulas and double-precision arithmetic, then display about seven significant figures. Real-world measurements carry uncertainty, so treat results as estimates unless your inputs are exact.